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KMID : 0378019880310010097
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New Medical Journal
1988 Volume.31 No. 1 p.97 ~ p.99
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Clinical Evaluation of Apagan^(®) in Obstetrics and Gynecology
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Abstract
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As pain is one of the most frequent symptoms in obstetric and gynecologic patients, so it is ve important to relieve pain at any condition. The purpose of this study is to evaluate the clinical analgesic efficacy and side effects of the polyvalent analgesic agent, Apagan®. 34 patients were included in this study, these are 6 postoperative patients, 16 pelvic inflammatory disease patients, 10 postpartum pat ents , and 2 dysmenorrhea patients.
The results were as follows:
1. There were excellent efficacy in 23 cases (67.6%), good efficacy in 7 cases (20.6%) and no imprivement in 4 cases (11.8%).
2. Side effects were observed in 6 cases (17.6%) but they were mild so that it was not necessary to top administration or to give other medication.
3. Apagan® drink seems to be markedly effective and safe analgesic in obstetrics and gynecolo? .The therapeutic efficacy of Hopa (Ca-Hopantenate; Hopate~´) was compared, with that of placel:o -in 7 5 patients with cerebrovascular diseases, with special reference to their effects on various mental symptoms, by a preparatory and.respective clinical,trial. 1.5mg Hopa was given a day for 6 weeks.
Subjective symptoms, Neurological findings; psychiatric symptoms and activity´of daily living (mainly ´ on reduced mental power and attention) were checked at the 6 week after medicatiop. 1. A considerable improvement in the clinical symptoms was achieved in 70.5 persents of cases with Hopa
with compared with 55.0 persents receiving the placebo.
2. Hopa produced significant improvement in the following factors, such as reduced spontaneity, atten
tion disorders and reduced initiatives in activities of daily living.
3. The side effects were mild and transient, and no abnormal laboratory finding related to test drugs was
noted.
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KEYWORD
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